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Zyprexa Diabetes: Excerpts From Public Reports Linking Olanzapine With Various Blood Sugar Disorders

The following emphasis-added excerpts are from public reports linking Zyprexa with diabetes, early onset diabetes, and diabetes mellitus:

Eli Lilly's best selling drug, olanzapine (Zyprexa), originally approved for schizophrenia, then for bi-polar disorder, is prescribed widely. But the drug has been shown to produce early onset diabetes, severe hyperglycemia--and deaths. Adolescents and young adults appear to be at particular risk.

On November 28, 2001, the Journal of the American Medical Association published a letter written by Dr. Elizabeth Koller, an FDA medical officer, Dr. P. Murali Doraiswamy, a Duke University psychiatrist warning that according to FDA's MedWatch data, patients taking either olanzapine or clozapine were 10 times more likely to become diabetic than the general population.
http://jama.ama-assn.org/issues/current/ffull/jlt1128-4.html Vol. 286 No. 20.

Those findings have been corroborated by several other studies. Yet, the FDA has done little to warn doctors and consumers. Patients taking the drug should, at the very least have their blood sugar monitored, but if doctors are unaware of the risk patients are not monitored.

National Alliance for the Mentally Ill, http://www.namiscc.org/News/2003/Summer/ZyprexaLinkToDiabetes.htm

Eli Lilly and Company would like to inform you of important labeling changes regarding Zyprexa (olanzapine). The Food and Drug Administration (FDA) has asked all manufacturers of atypical antipsychotic medications, including Lilly, to add a Warning statement describing the increased risk of hyperglycemia and diabetes in patients taking these medications, including Zyprexa. In addition to Zyprexa, the atypical antipsychotic class includes Clozaril ® (clozapine, Novartis), Risperdal ® (risperidone, Janssen), Seroquel ® (quetiapine, AstraZeneca), Geodon ® (ziprasidone, Pfizer), and Abilify ® (aripiprazole, Bristol Myers Squibb and Otsuka American Pharmaceutical).

Eli Lilly "Dear Doctor" Letter, http://www.fda.gov/medwatch/SAFETY/2004/zyprexa.htm

The researchers reported: "Of the 289 cases of diabetes linked to the use of olanzapine, 225 were newly diagnosed cases. One hundred patients developed ketosis (a serious complication of diabetes), and 22 people developed pancreatitis, or inflammation of the pancreas, which is a life-threatening condition. There were 23 deaths, including that of a 15-year-old adolescent who died of necrotizing pancreatitis, a condition where the pancreas breaks down and dies. Most cases (71 percent) occurred within six months of starting the drug and many cases were associated with moderate weight gain." The evidence from pre-marketing trials was also alarming: Whitaker wrote: "Of the 2,500 patients in the trials who received olanzapine, twenty died. Twelve killed themselves...Twenty-two percent [ ] suffered a 'serious' adverse event, compared to 18 percent of the haloperidol patients. Two-thirds of the olanzapine patients didn't successfully complete the trials...."(p. 281)

Alliance for Human Research Protectection, http://www.ahrp.org/infomail/0702/12b.php

If you think that Zyprexa* may have caused your diabetes (or other conditions) you are strongly encouraged to contact us. There is no charge, and no obligation. If we take your case, there is no fee for our services unless we win your case, or settle it in your favor. (Zyprexa is also commonly misspelled as "Zyprixa, Zyprexia, Zyphrexa, Zypexa, and Ziprexa.")

On the other hand, if you fail to protect your legal rights now, you may lose the right to be compensated for your harm. (Persons seeking to preserve any potential legal claims should contact an attorney promptly, since all states have mandatory time periods in which lawsuits must be filed with the courts; otherwise, they may be forever barred).

Our firm has a great deal of experience in representing plaintiffs in “drug” cases, and in fact, is currently pursuing numerous cases against "Vioxx," "Bextra" and “Metabolife."

In addition, we have the resources to handle our own cases. This means that when you call our firm, you talk to your own lawyer who has been assigned to your own case.

Please contact us now about Zyprexa and Diabetes . The secure form below only takes a couple of minutes to fill out, but if you are uncomfortable sending your information over the internet, please call our toll-free number at 800.921.1776 to speak to an attorney. The call is free, and there is no obligation. Act now, as delays can harm your case.

 

 

Important Notice: [^]

Persons seeking to preserve any potential legal claims should contact an attorney promptly, since all states have mandatory time periods in which lawsuits must be filed with the courts; otherwise, they may be forever barred.

About Our Firm: [^]

Alexander Hawes, LLP, an AV-rated trial firm, has concentrated its practice on the prosecution of complex Personal Injury and Class Action cases. The Firm represents individuals, governmental entities, businesses and institutional shareholders in auto accident cases, insurance claims, motorcycle injury accidents, and truck (and SUV) accidents. In addition, our law firm represents consumers in defective product, product liability, tort, negligence, mass tort, consumer, construction defect, investment fraud, price fixing and employment cases. The Firm is currently involved in complex cases pending in federal and state courts throughout the Unites States. The Firm is dedicated to quality representation of its clients and prides itself on aggressive advocacy of its clients' claims.

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