Bisphosphonates and Osteonecrosis of the Jaw - Free Information - Alexander Hawes, LLP

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Fosamax Lawsuit Information: Merck Fosamax Prescribing Information

The following information is from Merck's prescribing information for Doctors:

Osteonecrosis of the jaw, generally associated with tooth extraction and/or local infection, often with delayed healing, has been reported in patients taking bisphosphonates. Most reported cases of bisphosphonate-associated osteonecrosis have been in cancer patients treated with intravenous bisphosphonates, but some have occurred in patients with postmenopausal osteoporosis. Known risk factors for osteonecrosis include a diagnosis of cancer, concomitant therapies (e.g., chemotherapy, radiotherapy, corticosteroids), poor oral hygiene, and co-morbid disorders (e.g., pre-existing dental disease, anemia, coagulopathy, infection).

Patients who develop osteonecrosis of the jaw (ONJ) while on bisphosphonate therapy should receive care by an oral surgeon. Dental surgery may exacerbate the condition. For patients requiring dental rocedures, there are no data available to suggest whether discontinuation of bisphosphonate treatment reduces the risk for ONJ. Clinical judgment of the treating physician should guide the management plan of each patient based on individual benefit/risk assessment.

### end of Merck document

If you have taken Fosamax in the past, and you have suffered any serious complication, you have certain legal rights, and you may have a legal case against Merck, the maker of Fosamax. You should thus contact an Fosamax lawyer as soon as possible.

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